Linkage of NAMPT promoter variants to eNAMPT secretion, plasma eNAMPT levels, and ARDS severity

BACKGROUND AND OBJECTIVES: eNAMPT (extracellular nicotinamide phosphoribosyltransferase), a novel DAMP and TLR4 ligand, is a druggable ARDS therapeutic target with NAMPT promoter SNPs associated with ARDS severity. This study assesses the previously unknown influence of NAMPT promoter SNPs on NAMPT...

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Detalles Bibliográficos
Autores principales: Lynn, Heather, Sun, Xiaoguang, Casanova, Nancy G., Bime, Christian, Reyes Hernon, Vivian, Lanham, Clayton, Oita, Radu C., Ramos, Nikolas, Sun, Belinda, Coletta, Dawn K., Camp, Sara M., Karnes, Jason H., Ellis, Nathan A., Garcia, Joe G.N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363883/
https://www.ncbi.nlm.nih.gov/pubmed/37477094
http://dx.doi.org/10.1177/17534666231181262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363883/
https://www.ncbi.nlm.nih.gov/pubmed/37477094
http://dx.doi.org/10.1177/17534666231181262

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