Robust enhancer-gene regulation identified by single-cell transcriptomes and epigenomes

Single-cell sequencing could help to solve the fundamental challenge of linking millions of cell-type-specific enhancers with their target genes. However, this task is confounded by patterns of gene co-expression in much the same way that genetic correlation due to linkage disequilibrium confounds f...

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Detalles Bibliográficos
Autores principales: Xie, Fangming, Armand, Ethan J., Yao, Zizhen, Liu, Hanqing, Bartlett, Anna, Behrens, M. Margarita, Li, Yang Eric, Lucero, Jacinta D., Luo, Chongyuan, Nery, Joseph R., Pinto-Duarte, Antonio, Poirion, Olivier B., Preissl, Sebastian, Rivkin, Angeline C., Tasic, Bosiljka, Zeng, Hongkui, Ren, Bing, Ecker, Joseph R., Mukamel, Eran A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Short Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363915/
https://www.ncbi.nlm.nih.gov/pubmed/37492103
http://dx.doi.org/10.1016/j.xgen.2023.100342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363915/
https://www.ncbi.nlm.nih.gov/pubmed/37492103
http://dx.doi.org/10.1016/j.xgen.2023.100342

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