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Robust enhancer-gene regulation identified by single-cell transcriptomes and epigenomes
Single-cell sequencing could help to solve the fundamental challenge of linking millions of cell-type-specific enhancers with their target genes. However, this task is confounded by patterns of gene co-expression in much the same way that genetic correlation due to linkage disequilibrium confounds f...
Autores principales: | Xie, Fangming, Armand, Ethan J., Yao, Zizhen, Liu, Hanqing, Bartlett, Anna, Behrens, M. Margarita, Li, Yang Eric, Lucero, Jacinta D., Luo, Chongyuan, Nery, Joseph R., Pinto-Duarte, Antonio, Poirion, Olivier B., Preissl, Sebastian, Rivkin, Angeline C., Tasic, Bosiljka, Zeng, Hongkui, Ren, Bing, Ecker, Joseph R., Mukamel, Eran A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363915/ https://www.ncbi.nlm.nih.gov/pubmed/37492103 http://dx.doi.org/10.1016/j.xgen.2023.100342 |
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