Multi-layered genetic approaches to identify approved drug targets

Drugs targeting genes linked to disease via evidence from human genetics have increased odds of approval. Approaches to prioritize such genes include genome-wide association studies (GWASs), rare variant burden tests in exome sequencing studies (Exome), or integration of a GWAS with expression/prote...

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Detalles Bibliográficos
Autores principales: Sadler, Marie C., Auwerx, Chiara, Deelen, Patrick, Kutalik, Zoltán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363916/
https://www.ncbi.nlm.nih.gov/pubmed/37492104
http://dx.doi.org/10.1016/j.xgen.2023.100341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363916/
https://www.ncbi.nlm.nih.gov/pubmed/37492104
http://dx.doi.org/10.1016/j.xgen.2023.100341

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