Effects of bergapten on the pharmacokinetics of macitentan in rats both in vitro and in vivo

Macitentan was approved by the United States Food and Drug Administration (FDA) in 2013 for the treatment of pulmonary arterial hypertension (PAH). Bergapten is a furanocoumarin that is abundant in Umbelliferae and Rutaceae plants and is widely used in many Chinese medicine prescriptions. Considerin...

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Detalles Bibliográficos
Autores principales: Xu, Jia, Zhou, Quan, Hou, Pengjiao, Wang, Yu, Geng, Peiwu, Lu, Zebei, Zhou, Yunfang, Dai, Dapeng, Wang, Shuanghu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363979/
https://www.ncbi.nlm.nih.gov/pubmed/37492094
http://dx.doi.org/10.3389/fphar.2023.1204649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363979/
https://www.ncbi.nlm.nih.gov/pubmed/37492094
http://dx.doi.org/10.3389/fphar.2023.1204649

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