Circulating macrophages as the mechanistic link between mosaic loss of Y-chromosome and cardiac disease

BACKGROUND: Genetics evidences have long linked mosaic loss of Y-chromosome (mLOY) in peripheral leukocytes with a wide range of male age-associated diseases. However, a lack of cellular and molecular mechanistic explanations for this link has limited further investigation into the relationship betw...

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Detalles Bibliográficos
Autores principales: Xu, Xuehong, Zhou, Rong, Duan, Qinchun, Miao, Yuanlin, Zhang, Tingting, Wang, Mofei, Jones, Odell D., Xu, MengMeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Highlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10364353/
https://www.ncbi.nlm.nih.gov/pubmed/37488646
http://dx.doi.org/10.1186/s13578-023-01075-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10364353/
https://www.ncbi.nlm.nih.gov/pubmed/37488646
http://dx.doi.org/10.1186/s13578-023-01075-7

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