Repurposing thioridazine for inducing immunogenic cell death in colorectal cancer via eIF2α/ATF4/CHOP and secretory autophagy pathways

BACKGROUND: Colorectal cancer (CRC) is a highly prevalent cancer type with limited targeted therapies available and 5-year survival rate, particularly for late-stage patients. There have been numerous attempts to repurpose drugs to tackle this problem. It has been reported that autophagy inducers co...

Descripción completa

Detalles Bibliográficos
Autores principales: Tran, Thu-Ha, Kao, Ming, Liu, Hsiao-Sheng, Hong, Yi-Ren, Su, Yeu, Huang, Chi-Ying F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10364410/
https://www.ncbi.nlm.nih.gov/pubmed/37488534
http://dx.doi.org/10.1186/s12964-023-01190-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10364410/
https://www.ncbi.nlm.nih.gov/pubmed/37488534
http://dx.doi.org/10.1186/s12964-023-01190-5

Ejemplares similares