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Repurposing thioridazine for inducing immunogenic cell death in colorectal cancer via eIF2α/ATF4/CHOP and secretory autophagy pathways

BACKGROUND: Colorectal cancer (CRC) is a highly prevalent cancer type with limited targeted therapies available and 5-year survival rate, particularly for late-stage patients. There have been numerous attempts to repurpose drugs to tackle this problem. It has been reported that autophagy inducers co...

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Detalles Bibliográficos
Autores principales:	Tran, Thu-Ha, Kao, Ming, Liu, Hsiao-Sheng, Hong, Yi-Ren, Su, Yeu, Huang, Chi-Ying F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10364410/ https://www.ncbi.nlm.nih.gov/pubmed/37488534 http://dx.doi.org/10.1186/s12964-023-01190-5

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