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Prioritizing genes associated with brain disorders by leveraging enhancer-promoter interactions in diverse neural cells and tissues

BACKGROUND: Prioritizing genes that underlie complex brain disorders poses a considerable challenge. Despite previous studies have found that they shared symptoms and heterogeneity, it remained difficult to systematically identify the risk genes associated with them. METHODS: By using the CAGE (Cap...

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Detalles Bibliográficos
Autores principales: Zhao, Xingzhong, Song, Liting, Yang, Anyi, Zhang, Zichao, Zhang, Jinglong, Yang, Yucheng T., Zhao, Xing-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10364416/
https://www.ncbi.nlm.nih.gov/pubmed/37488639
http://dx.doi.org/10.1186/s13073-023-01210-6