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Small extracellular vesicles-transported lncRNA TDRKH-AS1 derived from AOPPs-treated trophoblasts initiates endothelial cells pyroptosis through PDIA4/DDIT4 axis in preeclampsia

BACKGROUND: Substantial studies have demonstrated that oxidative stress placenta and endothelial injury are considered to inextricably critical events in the pathogenesis of preeclampsia (PE). Systemic inflammatory response and endothelial dysfunction are induced by the circulating factors released...

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Detalles Bibliográficos
Autores principales: Chen, Qian, He, Jiexing, Liu, Haihua, Huang, Qiuyu, Wang, Shuoshi, Yin, Ailan, Chen, Shuying, Shen, Xinyang, Xiao, Yanxuan, Hu, Haoyue, Jiang, Jiayi, Chen, Wenqian, Wang, Song, Huang, Zhenqin, Li, Jiaqi, Peng, You, Wang, Xiaocong, Yang, Xinping, Wang, Zhijian, Zhong, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10364420/
https://www.ncbi.nlm.nih.gov/pubmed/37488572
http://dx.doi.org/10.1186/s12967-023-04346-6