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Enzymatic blood group conversion of human kidneys during ex vivo normothermic machine perfusion

A major restriction to transplantation is the requirement for ABO blood group compatibility between donor and recipient. In this study, an α-galactosidase enzyme from Bacteroides fragilis was used successfully to remove type B blood group antigens enzymatically from human kidneys using ex vivo normo...

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Detalles Bibliográficos
Autores principales: MacMillan, Serena, Hosgood, Sarah A, Nicholson, Michael L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10364487/
https://www.ncbi.nlm.nih.gov/pubmed/36038141
http://dx.doi.org/10.1093/bjs/znac293