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Enzymatic blood group conversion of human kidneys during ex vivo normothermic machine perfusion
A major restriction to transplantation is the requirement for ABO blood group compatibility between donor and recipient. In this study, an α-galactosidase enzyme from Bacteroides fragilis was used successfully to remove type B blood group antigens enzymatically from human kidneys using ex vivo normo...
Autores principales: | MacMillan, Serena, Hosgood, Sarah A, Nicholson, Michael L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10364487/ https://www.ncbi.nlm.nih.gov/pubmed/36038141 http://dx.doi.org/10.1093/bjs/znac293 |
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