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New insights into cancer: MDM2 binds to the citrullinating enzyme PADI4
PADI4 is one of the human isoforms of a family of enzymes implicated in the conversion of arginine to citrulline. MDM2 is an E3 ubiquitin ligase which is crucial for down‐regulation of degradation of the tumor suppressor gene p53. Given the relationship between both PADI4 and MDM2 with p53‐signaling...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10364586/ https://www.ncbi.nlm.nih.gov/pubmed/37409874 http://dx.doi.org/10.1002/pro.4723 |