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Transplantation of gut microbiota from old mice into young healthy mice reduces lean mass but not bone mass

Aging is associated with low bone and lean mass as well as alterations in the gut microbiota (GM). In this study, we determined whether the reduced bone mass and relative lean mass observed in old mice could be transferred to healthy young mice by GM transplantation (GMT). GM from old (21-month-old)...

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Detalles Bibliográficos
Autores principales: Lawenius, Lina, Cowardin, Carrie, Grahnemo, Louise, Scheffler, Julia M., Horkeby, Karin, Engdahl, Cecilia, Wu, Jianyao, Vandenput, Liesbeth, Koskela, Antti, Tukkanen, Juha, Coward, Eivind, Hveem, Kristian, Langhammer, Arnulf, Abrahamsson, Sanna, Gordon, Jeffrey I., Sjögren, Klara, Ohlsson, Claes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10364652/
https://www.ncbi.nlm.nih.gov/pubmed/37475479
http://dx.doi.org/10.1080/19490976.2023.2236755