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Antibiotics versus placebo in adults with CT-confirmed uncomplicated acute appendicitis (APPAC III): randomized double-blind superiority trial

BACKGROUND: Non-operative management of uncomplicated acute appendicitis is an option, but omission of antibiotics from the regimen has not been tested. METHODS: A double-blind, placebo-controlled, superiority RCT in adults with CT-confirmed uncomplicated acute appendicitis was designed to compare p...

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Detalles Bibliográficos
Autores principales: Salminen, Paulina, Sippola, Suvi, Haijanen, Jussi, Nordström, Pia, Rantanen, Tuomo, Rautio, Tero, Sallinen, Ville, Löyttyniemi, Eliisa, Hurme, Saija, Tammilehto, Ville, Laukkarinen, Johanna, Savolainen, Heini, Meriläinen, Sanna, Leppäniemi, Ari, Grönroos, Juha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10364767/
https://www.ncbi.nlm.nih.gov/pubmed/35576384
http://dx.doi.org/10.1093/bjs/znac086