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Cytokine-Mediated Degradation of the Transcription Factor ERG Impacts the Pulmonary Vascular Response to Systemic Inflammatory Challenge

During infectious diseases, proinflammatory cytokines transiently destabilize interactions between adjacent vascular endothelial cells (ECs) to facilitate the passage of immune molecules and cells into tissues. However, in the lung, the resulting vascular hyperpermeability can lead to organ dysfunct...

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Detalles Bibliográficos
Autores principales: Schafer, Christopher M., Martin-Almedina, Silvia, Kurylowicz, Katarzyna, Dufton, Neil, Osuna-Almagro, Lourdes, Wu, Meng-Ling, Johnson, Charmain F., Shah, Aarti V., Haskard, Dorian O., Buxton, Andrianna, Willis, Erika, Wheeler, Kate, Turner, Sean, Chlebicz, Magdalena, Scott, Rizaldy P., Kovats, Susan, Cleuren, Audrey, Birdsey, Graeme M., Randi, Anna M., Griffin, Courtney T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10364964/
https://www.ncbi.nlm.nih.gov/pubmed/37317853
http://dx.doi.org/10.1161/ATVBAHA.123.318926