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Huntingtin recruits KIF1A to transport synaptic vesicle precursors along the mouse axon to support synaptic transmission and motor skill learning

Neurotransmitters are released at synapses by synaptic vesicles (SVs), which originate from SV precursors (SVPs) that have traveled along the axon. Because each synapse maintains a pool of SVs, only a small fraction of which are released, it has been thought that axonal transport of SVPs does not af...

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Detalles Bibliográficos
Autores principales: Vitet, Hélène, Bruyère, Julie, Xu, Hao, Séris, Claire, Brocard, Jacques, Abada, Yah-Sé, Delatour, Benoît, Scaramuzzino, Chiara, Venance, Laurent, Saudou, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10365837/
https://www.ncbi.nlm.nih.gov/pubmed/37431882
http://dx.doi.org/10.7554/eLife.81011