Modulation of Extravascular Binding of Recombinant Factor IX Impacts the Duration of Efficacy in Mouse Models

Background  There is an emerging concept that in addition to circulating coagulation factor IX (FIX), extravascular FIX contributes to hemostasis. Objective  Our objective was to evaluate the efficacy of extravascular FIX using animal models of tail clip bleeding and ferric chloride-induced thrombos...

Descripción completa

Detalles Bibliográficos
Autores principales: Machado, Steffi Knoll, Peil, Hendrik, Kraushaar, Timo, Claar, Philipp, Mischnik, Marcel, Lind, Holger, Herzog, Eva, Bacher, Michael, Nolte, Marc Wolfgang, Bielohuby, Maximilian, Pestel, Sabine, Ponnuswamy, Padmapriya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10365885/
https://www.ncbi.nlm.nih.gov/pubmed/37164314
http://dx.doi.org/10.1055/a-2090-9739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10365885/
https://www.ncbi.nlm.nih.gov/pubmed/37164314
http://dx.doi.org/10.1055/a-2090-9739

Ejemplares similares