Posttransplant MRD and T-cell chimerism status predict outcomes in patients who received allografts for AML/MDS

Allogeneic stem-cell transplant allows for the delivery of curative graft-versus-leukemia (GVL) in patients with acute myeloid leukemia/myelodysplasia (AML/MDS). Surveillance of T-cell chimerism, measurable residual disease (MRD) and blast HLA-DR expression may inform whether GVL effectiveness is re...

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Detalles Bibliográficos
Autores principales: Loke, Justin, McCarthy, Nicholas, Jackson, Aimee, Siddique, Shamyla, Hodgkinson, Andrea, Mason, John, Crawley, Charles, Gilleece, Maria, Peniket, Andrew, Protheroe, Rachel, Salim, Rahuman, Tholouli, Eleni, Wilson, Keith, Andrew, Georgia, Dillon, Richard, Khan, Naeem, Potter, Victoria, Krishnamurthy, Pramila, Craddock, Charles, Freeman, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Myeloid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10365943/
https://www.ncbi.nlm.nih.gov/pubmed/37058448
http://dx.doi.org/10.1182/bloodadvances.2022009493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10365943/
https://www.ncbi.nlm.nih.gov/pubmed/37058448
http://dx.doi.org/10.1182/bloodadvances.2022009493

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