Cargando…

PE-STOP: A versatile tool for installing nonsense substitutions amenable for precise reversion

The rapid advances in genome editing technologies have revolutionized the study of gene functions in cell or animal models. The recent generation of double-stranded DNA cleavage–independent base editors has been suitably adapted for interrogation of protein-coding genes on the basis of introducing p...

Descripción completa

Detalles Bibliográficos
Autores principales: Song, Ziguo, Zhang, Guiquan, Huang, Shuhong, Liu, Yao, Li, Guanglei, Zhou, Xianhui, Sun, Jiayuan, Gao, Pengfei, Chen, Yulin, Huang, Xingxu, Liu, Jianghuai, Wang, Xiaolong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10365944/
https://www.ncbi.nlm.nih.gov/pubmed/37343700
http://dx.doi.org/10.1016/j.jbc.2023.104942