Cargando…
MET 14外显子跳跃突变NSCLC靶向治疗专家共识
The mesenchymal-epithelial transition factor (MET) exon 14 skipping mutation is mainly caused by the loss of c-Cbl tyrosine binding site. This mutation could result in a decrease in the degradation rate of proteasome-mediated MET proteins, trigger continuous activation of downstream pathways, and ul...
| Formato: | Online Artículo Texto |
|---|---|
| Lenguaje: | English |
| Publicado: |
Editorial board of Chinese Journal of Lung Cancer
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10365964/ https://www.ncbi.nlm.nih.gov/pubmed/37488079 http://dx.doi.org/10.3779/j.issn.1009-3419.2023.102.19 |