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Participation bias in the UK Biobank distorts genetic associations and downstream analyses
While volunteer-based studies such as the UK Biobank have become the cornerstone of genetic epidemiology, the participating individuals are rarely representative of their target population. To evaluate the impact of selective participation, here we derived UK Biobank participation probabilities on t...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10365993/ https://www.ncbi.nlm.nih.gov/pubmed/37106081 http://dx.doi.org/10.1038/s41562-023-01579-9 |