Commensal bacteria weaken the intestinal barrier by suppressing epithelial neuropilin-1 and Hedgehog signaling

The gut microbiota influences intestinal barrier integrity through mechanisms that are incompletely understood. Here we show that the commensal microbiota weakens the intestinal barrier by suppressing epithelial neuropilin-1 (NRP1) and Hedgehog (Hh) signaling. Microbial colonization of germ-free mic...

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Detalles Bibliográficos
Autores principales: Pontarollo, Giulia, Kollar, Bettina, Mann, Amrit, Khuu, My Phung, Kiouptsi, Klytaimnistra, Bayer, Franziska, Brandão, Inês, Zinina, Valeriya V., Hahlbrock, Jennifer, Malinarich, Frano, Mimmler, Maximilian, Bhushan, Sudhanshu, Marini, Federico, Ruf, Wolfram, Belheouane, Meriem, Baines, John F., Endres, Kristina, Reba, Scott M., Raker, Verena K., Deppermann, Carsten, Welsch, Christoph, Bosmann, Markus, Soshnikova, Natalia, Chassaing, Benoit, Bergentall, Mattias, Sommer, Felix, Bäckhed, Fredrik, Reinhardt, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10365997/
https://www.ncbi.nlm.nih.gov/pubmed/37414930
http://dx.doi.org/10.1038/s42255-023-00828-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10365997/
https://www.ncbi.nlm.nih.gov/pubmed/37414930
http://dx.doi.org/10.1038/s42255-023-00828-5

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