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Simplified and highly-reliable automated production of [(18)F]FSPG for clinical studies

BACKGROUND: (S)-4-(3-(18)F-Fluoropropyl)-L-Glutamic Acid ([(18)F]FSPG) is a positron emission tomography (PET) tracer that specifically targets the cystine/glutamate antiporter (xc(−)), which is frequently overexpressed in cancer and several neurological disorders. Pilot studies examining the dosime...

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Detalles Bibliográficos
Autores principales: Lin, Mai, Ta, Robert T., Manning, H. Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366059/
https://www.ncbi.nlm.nih.gov/pubmed/37486582
http://dx.doi.org/10.1186/s41181-023-00200-8