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Bacteroides ovatus accelerates metformin-induced vitamin B12 deficiency in type 2 diabetes patients by accumulating cobalamin

Vitamin B12 (VB12) deficiency, which may lead to hematologic and neurologic symptoms, has been associated with metformin use, but the underlying mechanism is unclear. Here we report the B. ovatus as an effective VB12 catcher which was enriched in the type 2 diabetes patients suffered from VB12 defic...

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Detalles Bibliográficos
Autores principales: Chen, Manyun, Shu, Yan, Li, Qing, Kang, Zhiqiang, Liu, Tao, Zhou, Honghao, Huang, Weihua, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366088/
https://www.ncbi.nlm.nih.gov/pubmed/37488134
http://dx.doi.org/10.1038/s41522-023-00419-y