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Effect of plant produced Anti-hIL-6 receptor antibody blockade on pSTAT3 expression in human peripheral blood mononuclear cells

As a response to invasion by pathogens, the secretion of interleukin 6 (IL-6) which is a cytokine, activates IL-6/JAKs/STAT3 intracellular signaling via., phosphorylation. Over expression of pSTAT3 induces IL-6 positive feedback loop causing cytokine release syndrome or cytokine storm. Plants have g...

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Detalles Bibliográficos
Autores principales: Kaewbandit, Namthip, Malla, Ashwini, Boonyayothin, Wanuttha, Rattanapisit, Kaewta, Phetphoung, Thareeya, Pisuttinusart, Nuttapat, Strasser, Richard, Saetung, Rattana, Tawinwung, Supannikar, Phoolcharoen, Waranyoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366097/
https://www.ncbi.nlm.nih.gov/pubmed/37488213
http://dx.doi.org/10.1038/s41598-023-39106-5