Zfp296 knockout enhances chromatin accessibility and induces a unique state of pluripotency in embryonic stem cells

The Zfp296 gene encodes a zinc finger-type protein. Its expression is high in mouse embryonic stem cells (ESCs) but rapidly decreases following differentiation. Zfp296-knockout (KO) ESCs grew as flat colonies, which were reverted to rounded colonies by exogenous expression of Zfp296. KO ESCs could n...

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Detalles Bibliográficos
Autores principales: Miyazaki, Satsuki, Yamano, Hiroyuki, Motooka, Daisuke, Tashiro, Fumi, Matsuura, Takumi, Miyazaki, Tatsushi, Miyazaki, Jun-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366109/
https://www.ncbi.nlm.nih.gov/pubmed/37488353
http://dx.doi.org/10.1038/s42003-023-05148-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366109/
https://www.ncbi.nlm.nih.gov/pubmed/37488353
http://dx.doi.org/10.1038/s42003-023-05148-8

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