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Zfp296 knockout enhances chromatin accessibility and induces a unique state of pluripotency in embryonic stem cells

The Zfp296 gene encodes a zinc finger-type protein. Its expression is high in mouse embryonic stem cells (ESCs) but rapidly decreases following differentiation. Zfp296-knockout (KO) ESCs grew as flat colonies, which were reverted to rounded colonies by exogenous expression of Zfp296. KO ESCs could n...

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Detalles Bibliográficos
Autores principales:	Miyazaki, Satsuki, Yamano, Hiroyuki, Motooka, Daisuke, Tashiro, Fumi, Matsuura, Takumi, Miyazaki, Tatsushi, Miyazaki, Jun-ichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366109/ https://www.ncbi.nlm.nih.gov/pubmed/37488353 http://dx.doi.org/10.1038/s42003-023-05148-8

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