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Multidirectional characterization of cellular composition and spatial architecture in human multiple primary lung cancers

Multiple primary lung cancers (MPLCs) pose diagnostic and therapeutic challenges in clinic. Here, we orchestrated the cellular and spatial architecture of MPLCs by combining single-cell RNA-sequencing and spatial transcriptomics. Notably, we identified a previously undescribed sub-population of epit...

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Detalles Bibliográficos
Autores principales: Wang, Yawei, Chen, Di, Liu, Yu, Shi, Daiwang, Duan, Chao, Li, Jinghan, Shi, Xiang, Zhang, Yong, Yu, Zhanwu, Sun, Nan, Wang, Wei, Ma, Yegang, Xu, Xiaohan, Otkur, Wuxiyar, Liu, Xiaolong, Xia, Tian, Qi, Huan, Piao, Hai-long, Liu, Hong-Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366158/
https://www.ncbi.nlm.nih.gov/pubmed/37488117
http://dx.doi.org/10.1038/s41419-023-05992-w