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Anandamide modulates WNT-5A/BCL-2, IP3/NFATc1, and HMGB1/NF-κB trajectories to protect against mercuric chloride-induced acute kidney injury

Endocannabinoid anandamide (AEA) has a physiological role in regulating renal blood flow, whereas its analogs ameliorated renal ischemia/reperfusion injury. Nonetheless, the role of AEA against mercuric chloride (HgCl(2))-induced renal toxicity has not been unraveled. Rats were allocated into contro...

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Detalles Bibliográficos
Autores principales: Abdallah, Dalaal M., Kamal, Mahmoud M., Aly, Nour Eldin S., El-Abhar, Hanan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366223/
https://www.ncbi.nlm.nih.gov/pubmed/37488162
http://dx.doi.org/10.1038/s41598-023-38659-9