Neurotransmitter release progressively desynchronizes in induced human neurons during synapse maturation and aging

Rapid release of neurotransmitters in synchrony with action potentials is considered a key hardwired property of synapses. Here, in glutamatergic synapses formed between induced human neurons, we show that action potential-dependent neurotransmitter release becomes progressively desynchronized as sy...

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Detalles Bibliográficos
Autores principales: Uzay, Burak, Houcek, Aiden, Ma, Z. Zack, Konradi, Christine, Monteggia, Lisa M., Kavalali, Ege T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366341/
https://www.ncbi.nlm.nih.gov/pubmed/36701235
http://dx.doi.org/10.1016/j.celrep.2023.112042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366341/
https://www.ncbi.nlm.nih.gov/pubmed/36701235
http://dx.doi.org/10.1016/j.celrep.2023.112042

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