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Neurotransmitter release progressively desynchronizes in induced human neurons during synapse maturation and aging
Rapid release of neurotransmitters in synchrony with action potentials is considered a key hardwired property of synapses. Here, in glutamatergic synapses formed between induced human neurons, we show that action potential-dependent neurotransmitter release becomes progressively desynchronized as sy...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366341/ https://www.ncbi.nlm.nih.gov/pubmed/36701235 http://dx.doi.org/10.1016/j.celrep.2023.112042 |