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Exposing and exploiting host–parasite arms race clues in SARS-CoV-2: a principally new method for improved T cell immunogenicity prediction

Computational prediction of T cell epitopes is a crucial component in the development of novel vaccines. T cells in a healthy vertebrate host can recognize as non-self only those peptides that are present in the parasite’s proteins but absent in the host’s proteins. This principle enables us to dete...

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Detalles Bibliográficos
Autores principales: Flegr, Jaroslav, Králová Lesná, Ivana, Zahradník, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366408/
https://www.ncbi.nlm.nih.gov/pubmed/37497282
http://dx.doi.org/10.1093/biomethods/bpad011