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Full-length transcript alterations in human bronchial epithelial cells with U2AF1 S34F mutations

U2AF1 is one of the most recurrently mutated splicing factors in lung adenocarcinoma and has been shown to cause transcriptome-wide pre-mRNA splicing alterations; however, the full-length altered mRNA isoforms associated with the mutation are largely unknown. To better understand the impact U2AF1 ha...

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Detalles Bibliográficos
Autores principales: Soulette, Cameron M, Hrabeta-Robinson, Eva, Arevalo, Carlos, Felton, Colette, Tang, Alison D, Marin, Maximillian G, Brooks, Angela N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366530/
https://www.ncbi.nlm.nih.gov/pubmed/37487637
http://dx.doi.org/10.26508/lsa.202000641