Cargando…

Full-length transcript alterations in human bronchial epithelial cells with U2AF1 S34F mutations

U2AF1 is one of the most recurrently mutated splicing factors in lung adenocarcinoma and has been shown to cause transcriptome-wide pre-mRNA splicing alterations; however, the full-length altered mRNA isoforms associated with the mutation are largely unknown. To better understand the impact U2AF1 ha...

Descripción completa

Detalles Bibliográficos
Autores principales:	Soulette, Cameron M, Hrabeta-Robinson, Eva, Arevalo, Carlos, Felton, Colette, Tang, Alison D, Marin, Maximillian G, Brooks, Angela N
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Life Science Alliance LLC 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366530/ https://www.ncbi.nlm.nih.gov/pubmed/37487637 http://dx.doi.org/10.26508/lsa.202000641

Ejemplares similares

Full-length transcript characterization of SF3B1 mutation in chronic lymphocytic leukemia reveals downregulation of retained introns
por: Tang, Alison D., et al.
Publicado: (2020)

Nuclear retention of full-length HTT RNA is mediated by splicing factors MBNL1 and U2AF65
por: Sun, Xin, et al.
Publicado: (2015)

Functional significance of U2AF1 S34F mutations in lung adenocarcinomas
por: Esfahani, Mohammad S., et al.
Publicado: (2019)

Autofluorescence Detection of Bronchial Tumors With the D-Light/AF
por: Häußinger, K., et al.
Publicado: (1999)

Ribosome biogenesis is a downstream effector of the oncogenic U2AF1-S34F mutation
por: Akef, Abdalla, et al.
Publicado: (2020)

The U2AF1(S34F) mutation induces lineage-specific splicing alterations in myelodysplastic syndromes
por: Yip, Bon Ham, et al.
Publicado: (2017)

Representations of AF-algebras and of the group U (∞)
por: Strâtilâ, Şerban-Valentin, et al.
Publicado: (1975)

Stoichiometries of U2AF35, U2AF65 and U2 snRNP reveal new early spliceosome assembly pathways
por: Chen, Li, et al.
Publicado: (2017)

uPAR regulates bronchial epithelial repair in vitro and is elevated in asthmatic epithelium
por: Stewart, Ceri E, et al.
Publicado: (2011)

Wild-Type U2AF1 Antagonizes the Splicing Program Characteristic of U2AF1-Mutant Tumors and Is Required for Cell Survival
por: Fei, Dennis Liang, et al.
Publicado: (2016)

Detecting haplotype-specific transcript variation in long reads with FLAIR2
por: Tang, Alison D., et al.
Publicado: (2023)

A splice site-sensing conformational switch in U2AF2 is modulated by U2AF1 and its recurrent myelodysplasia-associated mutation
por: Warnasooriya, Chandani, et al.
Publicado: (2020)

U2AF1(S34/Q157) Variants Detected in cis Arise Sequentially in an MDS Patient With Serial Sequencing Spanning 18 Years
por: Ferrone, Christina K., et al.
Publicado: (2022)

Targeting of U2AF(65) to Sites of Active Splicing in the Nucleus
por: Gama-Carvalho, Margarida, et al.
Publicado: (1997)

RNA structure replaces the need for U2AF2 in splicing
por: Lin, Chien-Ling, et al.
Publicado: (2016)

Integrative Profiling of Alternative Splicing Induced by U2AF1 S34F Mutation in Lung Adenocarcinoma Reveals a Mechanistic Link to Mitotic Stress
por: Kim, Suyeon, et al.
Publicado: (2018)

Culture with apically applied healthy or disease sputum alters the airway surface liquid proteome and ion transport across human bronchial epithelial cells
por: Woodall, Maximillian, et al.
Publicado: (2021)

Identification of U2AF(35)-dependent exons by RNA-Seq reveals a link between 3′ splice-site organization and activity of U2AF-related proteins
por: Kralovicova, Jana, et al.
Publicado: (2015)

RECURRENT MUTATIONS IN THE U2AF1 SPLICING FACTOR IN MYELODYSPLASTIC SYNDROMES
por: Graubert, Timothy A., et al.
Publicado: (2011)

Anemia in myelofibrosis—prevalence, the U2AF1 connection, new treatments
por: Tefferi, Ayalew
Publicado: (2017)

Epithelial Resurfacing: The Bronchial Skin Peel
por: Shah, Pallav L., et al.
Publicado: (2020)

AFS Monitoring: The CERN AFS Console
por: Wiebalck, Arne
Publicado: (2008)

On the Function of Trans-Splicing: No Evidence for Widespread Proteome Diversification in Trypanosomes
por: Soulette, Cameron M, et al.
Publicado: (2019)

Prp8 positioning of U5 snRNA is linked to 5′ splice site recognition
por: MacRae, Andrew J., et al.
Publicado: (2018)

Eosinophils Promote Epithelial to Mesenchymal Transition of Bronchial Epithelial Cells
por: Yasukawa, Atsushi, et al.
Publicado: (2013)

Alternate deacylating specificities of the archaeal sirtuins Sir2Af1 and Sir2Af2
por: Ringel, Alison E, et al.
Publicado: (2014)

Full-Length Genome Sequences of Senecavirus A from Recent Idiopathic Vesicular Disease Outbreaks in U.S. Swine
por: Zhang, Jianqiang, et al.
Publicado: (2015)

Mug{AF}amar{AF}at Farn{AF}ats{AF}i == Farnatchi au bal masqué == Farnatchi at the masked ball /
por: Fayard, Roland
Publicado: (1997)

U2AF1 mutations alter splice site recognition in hematological malignancies
por: Ilagan, Janine O., et al.
Publicado: (2015)

Mutant U2AF1-expressing cells are sensitive to pharmacological modulation of the spliceosome
por: Shirai, Cara Lunn, et al.
Publicado: (2017)

Arabidopsis U2AF65 Regulates Flowering Time and the Growth of Pollen Tubes
por: Park, Hyo-Young, et al.
Publicado: (2019)

U2AF1 mutation types in primary myelofibrosis: phenotypic and prognostic distinctions
por: Tefferi, Ayalew, et al.
Publicado: (2018)

Comparative evaluation of full-length isoform quantification from RNA-Seq
por: Sarantopoulou, Dimitra, et al.
Publicado: (2021)

The effects of poly I:C stimulation of primary bronchial epithelial cells and TSLP secretion on CD34+ progenitor cell eosinophil and basophil differentiation
por: Yu, Ashley, et al.
Publicado: (2014)

Two Arabidopsis Splicing Factors, U2AF65a and U2AF65b, Differentially Control Flowering Time by Modulating the Expression or Alternative Splicing of a Subset of FLC Upstream Regulators
por: Lee, Hee Tae, et al.
Publicado: (2023)

Overophedning af partikelaccelerator var frygtet af forskere
Publicado: (2008)

Impaired Differentiation of Chronic Obstructive Pulmonary Disease Bronchial Epithelial Cells Grown on Bronchial Scaffolds
por: Hedström, Ulf, et al.
Publicado: (2021)

Structure of Full-length Drosophila Cryptochrome
por: Zoltowski, Brian D., et al.
Publicado: (2011)

Electrogram Morphology Recurrence and Cycle Length in AF Mapping: From Recurring Concepts to Clinical Practice?
por: Masè, Michela, et al.
Publicado: (2023)

Signal-Regulated Pre-mRNA Occupancy by the General Splicing Factor U2AF
por: Tisserant, Anne, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_08g1ku4cp2imdqhli65qfcgsaa