Extended cleavage specificities of human granzymes A and K, two closely related enzymes with conserved but still poorly defined functions in T and NK cell-mediated immunity

Granzymes A and K are two highly homologous serine proteases expressed by mammalian cytotoxic T cells (CTL) and natural killer cells (NK). Granzyme A is the most abundant of the different granzymes (gzms) expressed by these two cell types. Gzms A and K are found in all jawed vertebrates and are the...

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Detalles Bibliográficos
Autores principales: Aybay, Erdem, Ryu, Jinhye, Fu, Zhirong, Akula, Srinivas, Enriquez, Erika Mendez, Hallgren, Jenny, Wernersson, Sara, Olsson, Anna-Karin, Hellman, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366535/
https://www.ncbi.nlm.nih.gov/pubmed/37497217
http://dx.doi.org/10.3389/fimmu.2023.1211295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366535/
https://www.ncbi.nlm.nih.gov/pubmed/37497217
http://dx.doi.org/10.3389/fimmu.2023.1211295

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