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Preparation of a Sunitinib loaded microemulsion for ocular delivery and evaluation for the treatment of corneal neovascularization in vitro and in vivo

Background: Corneal neovascularization (CNV) is a pathological condition that can disrupt corneal transparency, thus harming visual acuity. However, there is no effective drug to treat CNV. Sunitinib (STB), a small-molecule multiple receptor tyrosine kinase inhibitor, was shown to have an effect on...

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Detalles Bibliográficos
Autores principales: Shi, Jieran, Yang, Jingjing, Xu, Haohang, Luo, Qing, Sun, Jun, Zhang, Yali, Liang, Zhen, Zhao, Ningmin, Zhang, Junjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366539/
https://www.ncbi.nlm.nih.gov/pubmed/37497104
http://dx.doi.org/10.3389/fphar.2023.1157084