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Effects of asparaginases and L-carnitine on Western-diet-induced hepatosteatosis in mice

Abstract Background: Asparaginases are common chemotherapeutic agents used for the treatment of acute lymphoblastic leukemia as a single or combinational therapy. Accompanying hepatotoxicity makes its use in elderly patients with pre-conditions, as obesity or other hepatopathies, difficult. Various...

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Detalles Bibliográficos
Autores principales: Ali Mahmoud Assar, Mona, Hüffel, Martina, Afify, Mamdouh, Weiskirchen, Ralf, Eisert, Albrecht, Tolba, Rene, Steitz, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366552/
https://www.ncbi.nlm.nih.gov/pubmed/37497390
http://dx.doi.org/10.12688/f1000research.75870.1