Development of a new drug candidate for the inhibition of Lassa virus glycoprotein and nucleoprotein by modification of evodiamine as promising therapeutic agents

The Lassa virus (LASV), an RNA virus prevalent in West and Central Africa, causes severe hemorrhagic fever with a high fatality rate. However, no FDA-approved treatments or vaccines exist. Two crucial proteins, LASV glycoprotein and nucleoprotein, play vital roles in pathogenesis and are potential t...

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Detalles Bibliográficos
Autores principales: Akash, Shopnil, Baeza, Javiera, Mahmood, Sajjat, Mukerjee, Nobendu, Subramaniyan, Vetriselvan, Islam, Md. Rezaul, Gupta, Gaurav, Rajakumari, Vinibha, Chinni, Suresh V., Ramachawolran, Gobinath, Saleh, Fayez M., Albadrani, Ghadeer M., Sayed, Amany A., Abdel-Daim, Mohamed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366616/
https://www.ncbi.nlm.nih.gov/pubmed/37497547
http://dx.doi.org/10.3389/fmicb.2023.1206872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366616/
https://www.ncbi.nlm.nih.gov/pubmed/37497547
http://dx.doi.org/10.3389/fmicb.2023.1206872

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