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Lens epithelial cell apoptosis and intracellular Ca(2+) increase in the presence of xanthurenic acid

BACKGROUND: Xanthurenic acid is an endogenous product of tryptophan degradation by indoleamine 2,3-dioxygenase (IDO). We have previously reported that IDO is present in mammalian lenses, and xanthurenic acid is accumulated in the lenses with aging. Here, we studied the involvement of xanthurenic aci...

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Detalles Bibliográficos
Autores principales: Malina, Halina, Richter, Christoph, Frueh, Beatrice, Hess, Otto M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC103667/
https://www.ncbi.nlm.nih.gov/pubmed/11934353
http://dx.doi.org/10.1186/1471-2415-2-1