Detection of Antibody-Dependent Cell-Mediated Cytotoxicity—Supporting Antibodies by NK-92-CD16A Cell Externalization of CD107a: Recognition of Antibody Afucosylation and Assay Optimization

Antibody-dependent cell-mediated cytotoxicity (ADCC) by natural killer (NK) lymphocytes eliminates cells infected with viruses. Anti-viral ADCC requires three components: (1) antibody; (2) effector lymphocytes with the Fc-IgG receptor CD16A; and (3) viral proteins in infected cell membranes. Fc-afuc...

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Detalles Bibliográficos
Autores principales: Cruz Amaya, Judith, Walcheck, Bruce, Smith-Gagen, Julie, Lombardi, Vincent C., Hudig, Dorothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366760/
https://www.ncbi.nlm.nih.gov/pubmed/37489366
http://dx.doi.org/10.3390/antib12030044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366760/
https://www.ncbi.nlm.nih.gov/pubmed/37489366
http://dx.doi.org/10.3390/antib12030044

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