Soluble TREM2 Concentrations in the Cerebrospinal Fluid Correlate with the Severity of Neurofibrillary Degeneration, Cognitive Impairment, and Inflammasome Activation in Alzheimer’s Disease

Background: Individuals with specific TREM2 gene variants that encode for a Triggering Receptor Expressed on Myeloid cells 2 have a higher prevalence of Alzheimer’s disease (AD). By interacting with amyloid and apolipoproteins, the TREM2 receptor regulates the number of myeloid cells, phagocytosis,...

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Detalles Bibliográficos
Autores principales: Španić Popovački, Ena, Babić Leko, Mirjana, Langer Horvat, Lea, Brgić, Klara, Vogrinc, Željka, Boban, Marina, Klepac, Nataša, Borovečki, Fran, Šimić, Goran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366813/
https://www.ncbi.nlm.nih.gov/pubmed/37489359
http://dx.doi.org/10.3390/neurolint15030053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366813/
https://www.ncbi.nlm.nih.gov/pubmed/37489359
http://dx.doi.org/10.3390/neurolint15030053

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