TAF15 regulates the BRD4/GREM1 axis and activates the gremlin-1-NF-κB pathway to promote OA progression

BACKGROUND: Anterior cruciate ligament (ACL) injury is recognized as a risk factor for osteoarthritis (OA) progression. Herein, the function of TAF15 in ACL injury-induced OA was investigated. METHODS: OA cell model and OA mouse model were established by interleukin-1 beta (IL-1β) stimulation and AC...

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Detalles Bibliográficos
Autores principales: Du, Xiufan, Xin, Ruomei, Chen, Xiaoyan, Wang, Guangji, Huang, Chunhang, Zhou, Kai, Zhang, Shunli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Regenerative Medicine 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366938/
https://www.ncbi.nlm.nih.gov/pubmed/37496731
http://dx.doi.org/10.1016/j.reth.2023.06.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366938/
https://www.ncbi.nlm.nih.gov/pubmed/37496731
http://dx.doi.org/10.1016/j.reth.2023.06.016

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