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TAF15 regulates the BRD4/GREM1 axis and activates the gremlin-1-NF-κB pathway to promote OA progression
BACKGROUND: Anterior cruciate ligament (ACL) injury is recognized as a risk factor for osteoarthritis (OA) progression. Herein, the function of TAF15 in ACL injury-induced OA was investigated. METHODS: OA cell model and OA mouse model were established by interleukin-1 beta (IL-1β) stimulation and AC...
Autores principales: | Du, Xiufan, Xin, Ruomei, Chen, Xiaoyan, Wang, Guangji, Huang, Chunhang, Zhou, Kai, Zhang, Shunli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japanese Society for Regenerative Medicine
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366938/ https://www.ncbi.nlm.nih.gov/pubmed/37496731 http://dx.doi.org/10.1016/j.reth.2023.06.016 |
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