Isoform-specific, Semi-quantitative Determination of Highly Homologous Protein Levels via CRISPR-Cas9-mediated HiBiT Tagging

Many protein families consist of multiple highly homologous proteins, whether they are encoded by different genes or originating from the same genomic location. Predominance of certain isoforms has been linked to various pathological conditions, such as cancer. Detection and relative quantification...

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Detalles Bibliográficos
Autores principales: Seiler, Kristina, Rafiq, Sreoshee, Tschan, Mario P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bio-Protocol 2023
Materias:
Methods Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366989/
https://www.ncbi.nlm.nih.gov/pubmed/37497448
http://dx.doi.org/10.21769/BioProtoc.4777

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366989/
https://www.ncbi.nlm.nih.gov/pubmed/37497448
http://dx.doi.org/10.21769/BioProtoc.4777

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