HDR-based CRISPR/Cas9-mediated Knockout of PD-L1 in C57BL/6 Mice

The immune-inhibitory molecule programmed cell death ligand 1 (PD-L1) has been shown to play a role in pathologies such as autoimmunity, infections, and cancer. The expression of PD-L1 not only on cancer cells but also on non-transformed host cells is known to be associated with cancer progression....

Descripción completa

Detalles Bibliográficos
Autores principales: Heeb, Laura V., Taskoparan, Betül, Katsoulas, Antonios, Beffinger, Michal, Clavien, Pierre-Alain, Kobold, Sebastian, Gupta, Anurag, Berg, Johannes Vom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bio-Protocol 2023
Materias:
Methods Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366997/
https://www.ncbi.nlm.nih.gov/pubmed/37497456
http://dx.doi.org/10.21769/BioProtoc.4724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366997/
https://www.ncbi.nlm.nih.gov/pubmed/37497456
http://dx.doi.org/10.21769/BioProtoc.4724

Ejemplares similares