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HDR-based CRISPR/Cas9-mediated Knockout of PD-L1 in C57BL/6 Mice

The immune-inhibitory molecule programmed cell death ligand 1 (PD-L1) has been shown to play a role in pathologies such as autoimmunity, infections, and cancer. The expression of PD-L1 not only on cancer cells but also on non-transformed host cells is known to be associated with cancer progression....

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Detalles Bibliográficos
Autores principales:	Heeb, Laura V., Taskoparan, Betül, Katsoulas, Antonios, Beffinger, Michal, Clavien, Pierre-Alain, Kobold, Sebastian, Gupta, Anurag, Berg, Johannes Vom
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bio-Protocol 2023
Materias:	Methods Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366997/ https://www.ncbi.nlm.nih.gov/pubmed/37497456 http://dx.doi.org/10.21769/BioProtoc.4724

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