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The recombinase activating genes: architects of immune diversity during lymphocyte development

The mature lymphocyte population of a healthy individual has the remarkable ability to recognise an immense variety of antigens. Instead of encoding a unique gene for each potential antigen receptor, evolution has used gene rearrangements, also known as variable, diversity, and joining gene segment...

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Detalles Bibliográficos
Autores principales: Braams, Merijn, Pike-Overzet, Karin, Staal, Frank J. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10367010/
https://www.ncbi.nlm.nih.gov/pubmed/37497222
http://dx.doi.org/10.3389/fimmu.2023.1210818