Cellular Exposure to Chloroacetanilide Herbicides Induces Distinct Protein Destabilization Profiles

[Image: see text] Herbicides in the widely used chloroacetanilide class harbor a potent electrophilic moiety, which can damage proteins through nucleophilic substitution. In general, damaged proteins are subject to misfolding. Accumulation of misfolded proteins compromises cellular integrity by disr...

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Detalles Bibliográficos
Autores principales: Quanrud, Guy M., Lyu, Ziqi, Balamurugan, Sunil V., Canizal, Carolina, Wu, Hoi-Ting, Genereux, Joseph C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10367052/
https://www.ncbi.nlm.nih.gov/pubmed/37427419
http://dx.doi.org/10.1021/acschembio.3c00338

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10367052/
https://www.ncbi.nlm.nih.gov/pubmed/37427419
http://dx.doi.org/10.1021/acschembio.3c00338

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