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Traceless Thioacid-Mediated Radical Cyclization of 1,6-Dienes

[Image: see text] Five-membered ring systems are ubiquitous throughout natural products and synthetic therapeutics, and thus, efficient methods to access this essential scaffold are required. Herein, we report the thioacid-mediated, 5-exo-trig cyclization of various 1,6-dienes, with high yields of u...

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Detalles Bibliográficos
Autores principales: Lynch, Dylan M., Nolan, Mark D., Williams, Conor, Van Dalsen, Leendert, Calvert, Susannah H., Dénès, Fabrice, Trujillo, Cristina, Scanlan, Eoin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10367065/
https://www.ncbi.nlm.nih.gov/pubmed/37418624
http://dx.doi.org/10.1021/acs.joc.3c00824